--- /dev/null
+[[!meta title="The saltiness of the sea breaks DNA in marine invertebrates: possible implications for animal evolution."]]
+[[!tag evolution repair]]
+
+Dmitrieva NI, Ferraris JD, Norenburg JL, Burg MB.
+
+Cell Cycle. 2006 Jun;5(12):1320-3. doi:10.4161/cc.5.12.2867
+
+The saltiness of the sea breaks DNA in marine invertebrates: possible implications for animal evolution.
+
+[[!pmid 16775417 desc="Proposes that increased salinity in evaporating seas during the Cambrian caused elevated numbers of DNA breaks and accelerated evolution, leading to the Cambrian explosion. Vertebrates maintain constant interstitial osmolarity at ~300 mosmol/kg. Invertebrates show increased levels of DNA breaks (measured by TUNEL assay) at 1000 mosmol/kg compared to 300 mosmol/kg."]]