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+[[!meta title="Overcoming uncollapsed haplotypes in long-read assemblies of non-model organisms"]]
+[[!tag bioRxiv assembly benchmark]]
+
+Nadège Guiglielmoni, Antoine Houtain, Alessandro Derzelle, Karine van Doninck, Jean-François Flot
+
+bioRxiv 2020.03.16.993428; doi: https://doi.org/10.1101/2020.03.16.993428
+
+Overcoming uncollapsed haplotypes in long-read assemblies of non-model organisms
+
+[[!pmid 10.1101/2020.03.16.993428 desc="Benchark using a bdelloid rotifer. Performance of most software plateaus over 50× depth. purge_dups performed well on Flye assemblies. Filtering our shorter reads did not dramatically change the N50 of Flye 2.5 assemblies"]]
alternative to HaploMerger that takes read coverage into account when detecting
potential haplotigs. However, it does not merge haplotypes.
+`purge_dups`, another alternative tp HaploMerger and Purge Haplotivs, performed
+well on Flye 2.5 assemblies ([[Guiglielmoni and coll.,2020 |
+biblio/10.1101_2020.03.16.993428]]).
+
SALSA (Simple AssembLy ScAffolder, [[Ghurye and coll., 2017|biblio/28701198]])
takes Hi-C data and contigs as input and scaffolds them under the hypothesis
that most contact points are due to local (same-chromosome) proximity. Version