Café

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+[[!meta title="The evolutionary landscape of the Rab family in chordates."]]
+[[!tag Oikopleura]]
+
+Coppola U, Ristoratore F, Albalat R, D'Aniello S.
+
+Cell Mol Life Sci. 2019 Apr 26. doi:10.1007/s00018-019-03103-7
+
+The evolutionary landscape of the Rab family in chordates.
+
+[[!pmid 31028425 desc="“O. dioica lineage showed 11 additional losses, Rab4, Rab7L1, Rab9, Rab19/43, Rab21 Rab26/37, Rab28, Ift27, Rasef, EFcab4/Rab44 and RabX1. This species has, therefore, lost almost the 50% of the Rab toolkit, being the metazoan species with the smallest number of Rab subfamilies described so far.” “We detected [...] 5 independent duplications in O. dioica (Rab5/17, Rab6, Rab7, Rab10, Rab35).”  O. dioica lost the Rab-EF chimeras Rasef and EFcab4/44, but kept Rab46."]]

diff --git a/tags/Oikopleura.mdwn b/tags/Oikopleura.mdwn
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--- a/tags/Oikopleura.mdwn
+++ b/tags/Oikopleura.mdwn
@@ -165,6 +165,8 @@ Genes and pathways
    muscular arouse after the separation of the appendicularian and ascidian lineages,
    and 3 are cytoplasmic, one of them being intronless and possibly originated by
    retrotransposition.
+ - Duplications in the Rab family: Rab5/17, Rab6, Rab7, Rab10, Rab35.  The EF-Rab chimera
+   Rab46 is kept ([[Coppola and coll., 2019|biblio/31028425]]).  See below for the losses. 
 
 ### Lost
 
@@ -184,7 +186,9 @@ Genes and pathways
    et al., 2008|biblio/19030770]], [[Denoeud et al., 2010|biblio/21097902]]).
    It is found in _Ciona_ but not in _C. elegans_ ()[[Martz et al.,
    2008|biblio/19030770]].
-
+ - More than 50 % of the Rab family is lost ([[Coppola and coll., 2019|biblio/31028425]]):
+   Rab4, Rab7L1, Rab9, Rab19/43, Rab21 Rab26/37, Rab28, Ift27, RabX1 and the
+   the EF-rab chimera Rasef and EFcab4/Rab44.
 
 
 Transcriptome