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+[[!meta title="The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition."]]
+[[!tag ES metabolome]]
+
+Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A,
+Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG,
+Margaretha L, Robitaille AM, Margineantu D, Fiehn O, Hockenbery D, Blau CA,
+Raftery D, Margolin AA, Hawkins RD, Moon RT, Ware CB, Ruohola-Baker H.
+
+Nat Cell Biol. 2015 Dec;17(12):1523-35. doi:10.1038/ncb3264
+
+The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.
+
+[[!pmid 26571212 desc="A SAM sink in naive cells prevents deactivation of the Wnt pathway by repressor epigenetic methylations and activation of HIF pathway."]]